FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
osk
FlyBase ID
FBig0000107149
Interaction Network
Interactions Browser links
osk network
Reported Interactions
FBrf0229153-4.XC
Reference
Jeske et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
osk 

Oskar

self
osk 

Oskar

self
osk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
osk 
LOTUS domain
sufficient binding region
aa 139-240

coordinates relative to osk-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

(Jeske et al., 2015)
FBrf0229153-5.CH.MW
Reference
Jeske et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
osk 

Oskar

self
osk 

Oskar

self
osk 
osk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
osk 
LOTUS domain
sufficient binding region
aa 139-240

coordinates relative to osk-PA

osk 
LOTUS domain residue R215
mutation disrupting interaction
aa 215

R215E, coordinates relative to osk-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced as a recombinant fusion proteins in bacterial system.

(Jeske et al., 2015)
FBrf0235682-7.XC
Reference
Jeske et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
osk 

osk

self
osk 

osk

self
osk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
osk 
LOTUS domain
sufficient binding region
aa 139-240

coordinates relative to osk-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

(Jeske et al., 2017)

osk LOTUS domain and vas crystallize as an osk dimer with 2 vas molecules, each bound to an osk monomer on the opposite side of the dimer interface.

(Jeske et al., 2017)
External Crossreferences and Linkouts ( 0 )
References (2)