FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
LUBEL, Ubi-p63E
FlyBase ID
FBig0000107356
Interaction Network
Interactions Browser links
LUBEL network
Ubi-p63E network
Reported Interactions
FBrf0233890-1.PD.WB
Reference
Asaoka et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
LUBEL 

LUBEL

bait

GST tag

LUBEL 
Ubi-p63E 

Ub

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
LUBEL 
UBA2 domain
sufficient binding region
aa 2457-2513

coordinates relative to CG11321-PE

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey synthesized in vitro.

(Asaoka et al., 2016)

LUBEL binds to K48-linked and K63-linked di-ubiquitin chains, but not to M1-linked "linear"polyubiquitin chains.

(Asaoka et al., 2016)
FBrf0233890-3.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
LUBEL 

LUBEL

enzyme

GST tag

LUBEL 

LUBEL

enzyme

GST tag

LUBEL 
LUBEL 
LUBEL 
LUBEL 
LUBEL 
Ubi-p63E 

Ub

enzyme target
Ubi-p63E 

Ub

enzyme target
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)