FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
nwk
FlyBase ID
FBig0000108614
Interaction Network
Interactions Browser links
nwk network
Reported Interactions
FBrf0230460-1.PD.WB
Reference
Kelley et al., 2015
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
nwk 

Nwk

bait

SH3 domain, GST tag

nwk 

Nwk

prey

F-BAR domain, His tag

nwk 
nwk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
nwk 
F-BAR domain
sufficient binding region
aa 1-428

coordinates relative to nwk-PB

nwk 
SH3a domain
sufficient binding region
aa 547-601aa 640-696

coordinates relative to nwk-PB

coordinates relative to nwk-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Kelley et al., 2015)

The nwk F-BAR domain interacts with either of the two nwk SH3 domains.

(Kelley et al., 2015)
External Crossreferences and Linkouts ( 0 )
References (1)