FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000108844
Interaction Network
Interactions Browser links
His3 network
Ing3 network
Reported Interactions
FBrf0224612-3.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
His3 

H3

bait
His3 
Ing3 

dIng3

prey

GST tag

Ing3 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Ing3 
PHD domain
sufficient binding region
aa 608-684

coordinates relative to Ing3-PA

His3 
H3K4me3 site
necessary binding region
aa 4
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait peptide chemically synthesized; prey produced as a recombinant fusion protein in bacterial system.

Ing3 binds H3K4me3-modified His3, and to a lesser extent H3K4me2-modified His3. No interaction with K9 and K36 methylated peptides.

External Crossreferences and Linkouts ( 0 )
References (1)