FB2026_02 , released June 18, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Trl, MEP-1
FlyBase ID
FBig0000109259
Interaction Network
Interactions Browser links
Trl network
MEP-1 network
Reported Interactions
FBrf0235066-20.coIP.MS
Reference
Lomaev et al., 2017
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Trl 

GAF

bait
MEP-1 

MEP-1

prey

15 peptides identified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Lomaev et al., 2017)
FBrf0235066-7.Y2H
Reference
Lomaev et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Trl 

GAF

bait

fused to GAL4 DNA-binding domain

Trl 
MEP-1 

MEP-1

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Trl 
N-terminal region
sufficient binding region
aa 1-389

coordinates relative to Trl-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Lomaev et al., 2017)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Lomaev et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)