FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
vkg, sog
FlyBase ID
FBig0000109417
Interaction Network
Interactions Browser links
vkg network
sog network
Reported Interactions
FBrf0218813-2.PD.WB
Reference
Sawala et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
vkg 

vkg

bait

GST tag

sog 

sog

prey

Myc or V5 tag

sog 
sog 
sog 
sog 
sog 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
sog 
cysteine-rich domain 1
sufficient binding region
aa 95-186

coordinates relative to sog-PA

sog 
cysteine-rich domain 1 residues 138-141
mutation decreasing interaction
aa 138-141

KKRR to AAAA, coordinates relative to sog-PA

sog 
cysteine-rich domain 4
sufficient binding region
aa 935-1031

coordinates relative to sog-PA

sog 
cysteine-rich domain 4 residues 1020-1024
mutation decreasing interaction
aa 1020-1024

RRSRR to GGSGG, coordinates relative to sog-PA

sog 
cysteine-rich domain 4 residues 980-982,997-999
mutation decreasing interaction
aa 980-982,997-999

980RKR to AAA, 997KRR to AAA, coordinates relative to sog-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced from transfected construct.

(Sawala et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)