FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000111856
Interaction Network
Interactions Browser links
how network
stg network
Reported Interactions
FBrf0183830-1.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
stg 

string/cdc25

bait

biotin label

how 

how

prey

HA tag

how 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
how 
KH domain
mutation disrupting interaction
aa 185

R185C. Coordinates specific to all isoforms of how.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Authors used the long isoform of how in these experiments.

Interaction in vitro; bait produced and labeled by in vitro transcription; prey produced and labelled by in vitro translation.

FBrf0210446-2.coIP.PCR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
how 

HOW

bait
stg 

String

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

External Crossreferences and Linkouts ( 0 )
References (2)