FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
shn, Smr
FlyBase ID
FBig0000116167
Interaction Network
Interactions Browser links
shn network
Smr network
Reported Interactions
FBrf0207974-4.coIP.WB
Reference
Cai and Laughon, 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
shn 

Shn

bait

FLAG tag

shn 
shn 
shn 
shn 
Smr 

SMRTER

prey

HA tag

Smr 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
shn 
N-terminal domain
sufficient binding region
aa 1-273

coordinates relative to a 2527aa isoform

shn 
C-terminal domain
sufficient binding region
aa 1888-2527

coordinates relative to a 2527aa isoform

shn 
RD1 domain
mutation decreasing interaction
aa 253-273

deletion of RD1, coordinates relative to a 2527aa isoform

shn 
RD2 domain
mutation decreasing interaction
aa 590-603

deletion of RD2, coordinates relative to a 2527aa isoform

Smr 
interaction domain
sufficient binding region
aa 101-1192aa 261-1520
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Cai and Laughon, 2009)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)