FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Ilp2, Sdr
FlyBase ID
FBig0000117661
Interaction Network
Interactions Browser links
Ilp2 network
Sdr network
Reported Interactions
FBrf0220509-2.coIP.WB
Reference
Okamoto et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ilp2 

Dilp2

bait

His tag

Sdr 

SDR

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Sdr binds most Ilp proteins tested, except for Ilp4.

(Okamoto et al., 2013)

The Sdr and ImpL2 bind Ilp family proteins with different binding affinities.

(Okamoto et al., 2013)

Sdr and ImpL2 do not bind each other.

(Okamoto et al., 2013)

ImpL2 and Sdr compete for binding to Ilp2.

(Okamoto et al., 2013)

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Okamoto et al., 2013)
External Crossreferences and Linkouts ( 0 )
References (1)