FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Syt4, Syt1
FlyBase ID
FBig0000119839
Interaction Network
Interactions Browser links
Syt4 network
Syt1 network
Reported Interactions
FBrf0134720-4.PD.MW
Reference
Littleton et al., 2001
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Syt4 

synaptotagmin IV

bait

GST tag

Syt4 
Syt4 
Syt1 

synaptotagmin I

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syt4 
C2B domain residue 370
mutation decreasing interaction
aa 370

Y370N

Syt4 
C2B domain residues 385,386
mutation decreasing interaction
aa 385,386

K385A,K386A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as a recombinant fusion protein in bacterial system.

(Littleton et al., 2001)
External Crossreferences and Linkouts ( 0 )
References (1)