FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000119847
Interaction Network
Interactions Browser links
Sema1a network
Reported Interactions
FBrf0243223-1.XC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Sema1a

neutral component

His tag

Sema1a

neutral component

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
interaction domain
sufficient binding region
aa 21-602

21N-602Q

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Sema1a forms a dimer in crystallo.

Interaction in vitro; protein produced as a recombinant fusion protein in HEK293 cells.

FBrf0243223-8.CH.MW
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Sema1a

neutral component

His tag

Sema1a

neutral component

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
interaction domain
sufficient binding region
aa 21-606

21N-606E

interaction domain residue 227
mutation disrupting interaction
aa 227

C227S

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; protein produced as a recombinant fusion protein in HEK293 cells.

Sema1a exists in solution as a mixture of monomer and dimer.

FBrf0243223-9.CM.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Sema1a

neutral component

His tag

Sema1a

neutral component

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
interaction domain
sufficient binding region
aa 21-606

21N-606E

interaction domain residue 227
mutation disrupting interaction
aa 227

C227S

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Sema1a exists in solution as a mixture of monomer and dimer.

Interaction in vitro; protein produced as a recombinant fusion protein in HEK293 cells.

External Crossreferences and Linkouts ( 0 )
References (1)