FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Syt1, AP-2α
FlyBase ID
FBig0000119993
Interaction Network
Interactions Browser links
Syt1 network
AP-2α network
Reported Interactions
FBrf0134720-2.PD.WB
Reference
Littleton et al., 2001
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Syt1 

synaptotagmin I

bait

GST tag

Syt1 
AP-2α 

AP-2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syt1 
C2B domain
necessary binding region
aa 312-474

coordinates relative to Syt1-PA.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type head membranes.

(Littleton et al., 2001)
External Crossreferences and Linkouts ( 0 )
References (1)