FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Arr1, Mppe
FlyBase ID
FBig0000120091
Interaction Network
Interactions Browser links
Arr1 network
Mppe network
Reported Interactions
FBrf0243306-2.PD.MS
Reference
Mu et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Mppe 

dMPPE

bait

GST tag

Arr1 

Arr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from unspecified fly extract.

(Mu et al., 2019)
FBrf0243306-4.coIP.WB
Reference
Mu et al., 2019
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Mppe 

dMPPE

bait
Arr1 

Arr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mu et al., 2019)
FBrf0243306-5.PD.WB
Reference
Mu et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Arr1 

Arr1

bait

MBP tag

Mppe 

dMPPE

prey

GST tag

Mppe 
Mppe 
Mppe 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Mppe 
C-terminal domain
sufficient binding region
aa 230-355

coordinates relative to Mppe-PA

Mppe 
C-terminal domain
necessary binding region
aa 230-355

coordinates relative to Mppe-PA

Mppe 
C-terminal domain residues 344-352
mutation disrupting interaction
aa 344-352

residues mutated to alanine, coordinates relative to Mppe-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Mu et al., 2019)
External Crossreferences and Linkouts ( 0 )
References (1)