FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
glo, Fmr1
FlyBase ID
FBig0000120642
Interaction Network
Interactions Browser links
glo network
Fmr1 network
Reported Interactions
FBrf0246626-2.coIP.WB
Reference
Bansal et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

Glo

bait

GFP tag

Fmr1 

Fmr1

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Bansal et al., 2020)
FBrf0246626-36.coIP.MS
Reference
Bansal et al., 2020
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

Glo

bait

GFP tag

Fmr1 

Fmr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Bansal et al., 2020)
FBrf0255220-1.coIP.MS
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

glo

bait

GFP tag

Fmr1 

dFMRP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Peng and Gavis, 2022)

Fig1A-C

(Peng and Gavis, 2022)
FBrf0255220-2.coIP.WB
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

glo

bait

GFP tag

glo 
Fmr1 

dFMRP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
glo 
qRRM2 domain
necessary binding region
aa 145-232

Deletion construct.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Fig1E, Fig6A,B

(Peng and Gavis, 2022)

Source was ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Peng and Gavis, 2022)
FBrf0255220-3.coIP.WB
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

glo

bait
Fmr1 

dFMRP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

FigS1

(Peng and Gavis, 2022)

Source was ovaries of wild type line; bait and prey produced from endogenous gene.

(Peng and Gavis, 2022)
FBrf0255220-4.coIP.WB
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Fmr1 

dFMRP

bait

GFP tag

glo 

glo

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Peng and Gavis, 2022)

Fig1E

(Peng and Gavis, 2022)
FBrf0255220-7.PD.WB
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
glo 

glo

bait

His tag

glo 
Fmr1 

dFMRP

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
glo 
qRRM2 domain
sufficient binding region
aa 145-232
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced from tagged transgenic construct.

(Peng and Gavis, 2022)
FBrf0255220-8.CH.MW
Reference
Peng and Gavis, 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Fmr1 

dFMRP

neutral component

His tag

Fmr1 

dFMRP

neutral component

His tag

Fmr1 
Fmr1 

dFMRP

neutral component

His tag

Fmr1 
glo 

glo

neutral component

His ag

glo 
glo 

glo

neutral component

His ag

glo 

glo

neutral component

His ag

glo 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Fmr1 
interaction domain
sufficient binding region
aa 220-681

N-terminal deletion construct.

glo 
qRRM2 domain
sufficient binding region
aa 145-232
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced as a recombinant fusion proteins in bacterial system.

(Peng and Gavis, 2022)
External Crossreferences and Linkouts ( 0 )
References (2)