FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000120966
Interaction Network
Interactions Browser links
Snr1 network
Cdk2 network
Reported Interactions
FBrf0180290-1.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snr1 

SNR1

bait
Cdk2 

Cdk2

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Embryonic extracts were prepared from flies expressing MYC-tagged DmCDK2

Source was embryonic extracts; bait produced endogenous gene; prey derived from transgenic construct

FBrf0180290-4.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snr1 

SNR1

bait

GST tag

Snr1 
Cdk2 

Cdk2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Snr1 
interaction domain
sufficient binding region
aa 230-370230-31014-156

coordinates relative to Snr1-PA; strongest interaction

coordinates relative to Snr1-PA

coordinates relative to Snr1-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from transgenic construct.

Embryonic extracts were prepared from flies expressing MYC-tagged DmCDK2

FBrf0180290-7.Y2H
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cdk2 

CDK2

bait

Cdk2 protein (aa 2-315) fused to the LexA DNA-binding domain

Snr1 

SNR1

prey

Snr1 fused to the B42 activation domain

Snr1 
Snr1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Snr1 
interaction domain
mutation decreasing interaction
G256D

coordinates relative to Snr1-PA; mutation caused interaction decrease in full-length Snr1 (15-370)

Snr1 
interaction domain
sufficient binding region
aa 15-240aa 240-370

coordinates relative to Snr1-PA; interaction strongly reduced relative to full-length

coordinates relative to Snr1-PA; increased interaction relative to full-length

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein

External Crossreferences and Linkouts ( 0 )
References (1)