FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
RPA2, RPA1
FlyBase ID
FBig0000121560
Interaction Network
Interactions Browser links
RPA2 network
RPA1 network
Reported Interactions
FBrf0057831-1.CH.MW
Reference
Mitsis et al., 1993
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RPA1 

70 000 molecular weight peptide

neutral component
RPA1 

70 000 molecular weight peptide

neutral component
RPA1 

70 000 molecular weight peptide

neutral component
RPA1 

70 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
RPA2 

30 000 molecular weight peptide

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The D-SSB complex consists of RpA-8, RpA-30 and RpA-70, with estimated complex size of 102 kDa.

(Mitsis et al., 1993)

Interaction in vitro; proteins produced from endogenous genes.

(Mitsis et al., 1993)
FBrf0068586-1.CH.MW
Reference
Marton et al., 1994
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RPA1 

66 kDa polypeptide

neutral component
RPA1 

66 kDa polypeptide

neutral component
RPA1 

66 kDa polypeptide

neutral component
RPA1 

66 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
RPA2 

31 kDa polypeptide

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced from endogenous genes.

(Marton et al., 1994)
FBrf0083305-1.coIP.WB
Reference
Mitsis, 1995
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RPA2 

30-kDa subunit

bait
RPA2 

30-kDa subunit

bait
RPA1 

70-kDa subunit

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mitsis, 1995)
FBrf0218395-4769.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RPA1 
unspecified role
RPA1 
unspecified role
RPA1 
unspecified role
RPA1 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
RPA2 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 419.11657

External Crossreferences and Linkouts ( 0 )
References (4)