FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Hsap\APOL1, Syx7
FlyBase ID
FBig0000123069
Interaction Network
Interactions Browser links
Hsap\APOL1 network
Syx7 network
Reported Interactions
FBrf0257973-1.coIP.WB
Reference
Lee et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hsap\APOL1 

APOL1

bait

FLAG tag

Hsap\APOL1 
Hsap\APOL1 
Syx7 

Syx7

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Hsap\APOL1 
G1 SRA interaction domain residue 384 and 342
mutation decreasing interaction
aa 384

I384M and S342G.

Hsap\APOL1 
G2 SRA interaction domain residue 388 and 389
mutation decreasing interaction
aa 388-389

N388-_Y389 deletion.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Lee et al., 2023)
External Crossreferences and Linkouts ( 0 )
References (1)