FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
L2HGDH
FlyBase ID
FBig0000123110
Interaction Network
Interactions Browser links
L2HGDH network
Reported Interactions
FBrf0258689-1.PD.CH.SLS
Reference
Yang et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
L2HGDH 

L2HGDH

self

His tag

L2HGDH 
L2HGDH 

L2HGDH

self

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
L2HGDH 
interaction domain
sufficient binding region
aa 41-455

coordinates relative to L2HGDH-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

(Yang et al., 2024)
FBrf0258689-2.XC
Reference
Yang et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
L2HGDH 

L2HGDH

self

His tag

L2HGDH 

L2HGDH

self

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

L2HGDH forms a tetramer in complex with FAD and 2-OG.

(Yang et al., 2024)

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system.

(Yang et al., 2024)
External Crossreferences and Linkouts ( 0 )
References (1)