FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
me31B, muskelin
FlyBase ID
FBig0000123782
Interaction Network
Interactions Browser links
me31B network
muskelin network
Reported Interactions
FBrf0261924-1.coIP.WB
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
muskelin 

muskelin

bait
me31B 

me31B

prey

GFP

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

muskelin-me31B interaction is lost at the end of the maternal-to-zygotic transition (MZT) phase (4-5 AEL). Knockdown of UbcE2H restores muskelin-me31B interaction at 4-5 AEL.

(Briney et al., 2025)

Source was embryos of transgenic fly line; bait produced from endogenous gene; prey produced from transgenic construct.

(Briney et al., 2025)
FBrf0261924-10.coIP.MS
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
muskelin 

muskelin

bait

GFP

me31B 

me31B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Briney et al., 2025)

Knockdown of RanBPM results in loss of muskelin-me31B interaction.

(Briney et al., 2025)
FBrf0261924-13.coIP.MS
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
muskelin 

muskelin

bait

GFP

me31B 

me31B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cross-linking increases muskelin-me31B interaction.

(Briney et al., 2025)

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Briney et al., 2025)
FBrf0261924-16.coIP.WB
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
me31B 

me31B

bait
muskelin 

muskelin

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Briney et al., 2025)
FBrf0261924-17.coIP.MS
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
me31B 

me31B

bait
muskelin 

muskelin

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Briney et al., 2025)
FBrf0261924-2.coIP.WB
Reference
Briney et al., 2025
Description
physical association
Assay
Collection
Source/Stage
oocyte / oogenesis stage S14organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
me31B 

me31B

bait

GFP

muskelin 

muskelin

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos or oocytes of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Briney et al., 2025)
External Crossreferences and Linkouts ( 0 )
References (1)