FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
InR, Ilp2
FlyBase ID
FBig0000123978
Interaction Network
Interactions Browser links
InR network
Ilp2 network
Reported Interactions
FBrf0263732-4.EM
Reference
Cai et al., 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
InR 

InR

neutral component
InR 
InR 

InR

neutral component
InR 
InR 

InR

neutral component
Ilp2 

Ilp2

neutral component
Ilp2 

Ilp2

neutral component
Ilp2 

Ilp2

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
InR 
interaction domain
sufficient binding region
aa 1-50, 151-1675

coordinates relative to InR-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Ilp2 forms an asymetric conformation when bound to InR.

(Cai et al., 2025)

Interaction in vitro; InR produced as a recombinant fusion protein in a baculovirus system; Ilp2 chemically synthesized.

(Cai et al., 2025)
External Crossreferences and Linkouts ( 0 )
References (1)