FB2026_02 , released June 18, 2026
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Citation
Sofer, W.H., Hatkoff, M.A. (1972). Chemical selection of alcohol dehydrogenase negative mutants in Drosophila.  Genetics 72(): 545--549.
FlyBase ID
FBrf0023971
Publication Type
Research paper
Abstract
We describe a selection procedure which utilizes the vapor from an unsaturated alcohol, 1-pentene-3-ol, for the detection and isolation of mutant flies with little or no alcohol dehydrogenase activity. ADH-negative flies are unaffected by exposure to the unsaturated alcohol, but ADH positives (wild-types) die after short exposure. The technique can be used to select rare ADH-negative individuals from large populations of wild-type flies.
PubMed ID
PubMed Central ID
PMC1212853 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Genetics
    Title
    Genetics
    Publication Year
    1916-
    ISBN/ISSN
    0016-6731
    Data From Reference
    Genes (1)