Caggese, C., de Pinto, V., Ferrandino, A. (1982). Purification and genetic control of NAD-dependent glutamate dehydrogenase from Drosophila melanogaster.  Biochem. Genet. 20(5/6): 449--460.

FBrf0037510

Research paper

Glutamate dehydrogenase has been purified to near-homogeneity from mature larvae of Drosophila melanogaster. The enzyme has a molecular weight of 347,000 measured by sucrose gradient sedimentation and 343,000 measured by variable-porosity acrylamide gel electrophoresis. Electrophoresis under denaturing conditions showed that the enzyme consists of six subunits of molecular weight 57,000. The structural gene for GDH has been mapped at 81.7 +/- 0.8 on the third chromosome by means of an electrophoretic variant.