Munneke, L.R., Collier, G.E. (1985). Genetic and biochemical characterization of phosphofructokinase from Drosophila melanogaster.  Biochem. Genet. 23(): 847--857.

FBrf0041947

Research paper

Phosphofructokinase (PFK;EC 2.7.1.11) activity in Drosophila melanogaster is controlled by a single dosage-sensitive region of the genome between 45F and 47E of chromosome IIR. Only a single form of PFK was detected electrophoretically in both adults and larvae. Nearly 90% of the PFK activity in adults is localized to the thorax. Purification of the enzyme was hampered by the extreme lability of Drosophila PFK; however, a 36-fold partial purification was achieved.