FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Elkins, T., Ganetzky, B., Wu, C.F. (1986). A Drosophila mutation that eliminates a calcium-dependent potassium current.  Proc. Natl. Acad. Sci. U.S.A. 83(): 8415--8419.
FlyBase ID
FBrf0045280
Publication Type
Research paper
Abstract
A mutation of Drosophila, slowpoke (slo), specifically abolishes a Ca2+-dependent K+ current, IC, from dorsal longitudinal flight muscles of adult flies. Other K+ currents remain normal, providing evidence that IC is mediated by a molecularly distinguishable set of channels. The pharmacological properties of IC are similar to those of Ca2+-dependent currents in some vertebrate cells. The muscle action potential was significantly lengthened in slo flies, indicating that IC plays the major role in its repolarization.
PubMed ID
PubMed Central ID
PMC386939 (PMC) (EuropePMC)
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Proc. Natl. Acad. Sci. U.S.A.
    Title
    Proceedings of the National Academy of Sciences of the United States of America
    Publication Year
    1915-
    ISBN/ISSN
    0027-8424
    Data From Reference
    Genes (1)