FB2026_03 , released September 17, 2026
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Citation
Bargiello, T.A., Saez, L., Baylies, M.K., Gasic, G., Young, M.W., Spray, D.C. (1987). The Drosophila clock gene per affects intercellular junctional communication.  Nature 328(): 686--691.
FlyBase ID
FBrf0047076
Publication Type
Research paper
Abstract
The per locus of Drosophila has been implicated in the control of behavioural rhythms. In fruitfly embryos and larvae per is expressed in salivary glands. Per mutations have striking effects on intercellular communication in salivary glands: gap junction channels are modulated so that their conductance varies inversely with the period of behavioural rhythms in the mutants. A similar effect on junctional communication in the nervous system may explain how per influences behavioural rhythms.
PubMed ID
2441265
PubMed Central ID
DOI
10.1038/328686a0
Related Publication(s)
Retraction

per: no link to gap junctions. Retraction.
Bargiello et al., 1992, Nature 360(6404): 542 [FBrf0059114]

Associated Information
Comments

THIS PAPER HAS BEEN RETRACTED, see the associated retraction FBrf0225457, which states that the authors wish to retract those portions of the paper "reporting evidence for the involvement of per in gap-junction-mediated intercellular communication". Other aspects of the paper remain valid.

Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nature
    Title
    Nature
    Publication Year
    1869-
    ISBN/ISSN
    0028-0836
    Data From Reference
    Alleles (1)
    Genes (1)