Jaynes, J.B., O'Farrell, P.H. (1988). Activation and repression of transcription by homeodomain-containing proteins that bind a common site.  Nature 336(): 744--749.

FBrf0048776

Research paper

The product of the fushi tarazu (ftz) gene is shown to be a site-dependent activator of transcription. In vitro-defined binding sites act as ftz-dependent enhancers in cultured cells. Another homoeodomain-containing protein, the engrailed gene product, competes for homoeodomain-binding sites and counteracts ftz activation.

PMC2868829 (PMC) (EuropePMC)