Glushkova, I.V., Belyaeva, E.S., Gvozdev, V.A. (1991). Podderzhanie chisla kopii retrotranspozona MDG3 v genome Drosophila melanogaster. [Maintenance of copy number of retrotransposon MDG3 in Drosophila melanogaster.]  Genetika, Moscow 27: 404--410.

FBrf0054216

Research paper

The genomes of laboratory stocks and natural population of Drosophila melanogaster contain 8-12 copies of retrotransposon MDG3 detected by in situ hybridization. Construction of genotypes with decreased MDG3 copy number using X-chromosome and chromosome 3 free of MDG3 copies results in appearance of hybrid genomes carrying up to 7-10 copies, instead of 2-4 copies expected. New MDG3 copies are detected in different genome regions, including the 42B hot spot of their location. The chromosomes, where new clusters of MDG3 were observed, carry conserved "parental pattern" of MDG1 arrangement. The data obtained suggest the existence of genomic mechanism for maintenance of retrotransposon copy number on a definite level.