Abstract
1. The activity of l-glutamate dehydrogenase isolated from larvae of two strains of Drosophila melanogaster has been investigated as a function of various parameters, and compared with that of the beef liver enzyme.
2. The pH dependence and most of the kinetic parameters of the insect enzymes are very similar to those of the beef liver GDH.
3. The most characteristic features of Drosophila enzymes are an early (∼30°C) temperature inactivation and a very low reactivity with NADP.