Name: Karen L. Schulze
Address:
Division of Neuroscience, Baylor College of Medicine,
One Baylor Plz., Houston TX 77030 USA
Corrections to FlyBase ID No. FBgn0013343
Gene Symbol syx1A
Data from references FBrf0078115 and NEW
Phenotypic info:
Broadie et al., 1995, Neuron  15:663-673  (NEW reference)
Syx1A is absolutely required for spontaneous vesicle
fusions, for these events are absent in syx1A null mutants.
However, mature, docked synaptic vesicles are observed by
EM at release sites in the presynaptic terminals of syx1A
mutant synapses. Therefore, syntaxin functions downstream
of vesicle docking and participates in fusion.
Data from references FBrf0080377 and FBrf0079352
Phenotypic info:
The syx1A gene product plays a role in general secretion and
is required for exocytosis from a variety of secretory
tissues. Syx1A is absolutely required for evoked neuro-
transmission as lack of Syx1A entirely abolishes evoked
neurotransmitter release.
Data from references FBrf0080377 and NEW
synonym(s):
syx1A
syx
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Karen Schulze