Subject: Re: 57B homeodomains Rachel, Here's what I know about E97. We got a bit of 3' sequence from the homeobox region, but none that overlapped with the PPH17 sequence. In addition, the sequence was done only once and that sloppily, so was highly inaccurate . However, Dyana Dalton, a grad student in my lab, did cross hybridize Markus Noll's genomic clone containing PPH17 and our genomic clone containing the E97 homeobox. They didn't give a signal indicating sequence identity (besides a weak signal due to the homeobox homology), so we concluded that they are likely to be different homeobox loci in 57B1-5. Bill McGinnis