Subject: RE: groovin/kakapo
FlyBase currently has gene entries for both groovin and kakapo. 'groovin'
was initially defined as the antigen recognised by a monoclonal antibody
(in Volk and Vijay Raghavan, 1994, Development 120(1): 59--70), not a
mutant. This monoclonal still stains embryos deficient for the kakapo
gene, and homozyous mutant kakapo embryos. However the groovin monoclonal
antibody was used to isolate a cDNA which turns out to be a kakapo cDNA,
and the antibody recognizes an immunoprecipitated Kakapo protein, therefore
the antibody appears to recognise kakapo as well as other proteins.