Subject: hello again + Flybase info. Dear Rachel, . I'm writing now with a Flybase update. I wasn't sure who would be the best person to contact, but I figured that you could at least pass on the information to the appropriate party. It relates to a gene that we previously reported and that is listed in Flybase as 'heartbroken' (hbr). The original entry was based on an abstract in the 1997 U.S. Drosophila Conference. We have since published a paper on this gene -- Development 125, 4379-4389 (1998) but it's so recent that I have just seen it on the journal's website, not in print form. What is more interesting and not yet in the literature is that hbr is allelic to 'downstream of FGF receptor' (dof), a gene that was independently characterized (and in their case cloned) by Markus Affolter and Maria Leptin. The reference for their paper is Molecular Cell 2, 515-525 (1998). I checked Flybase but didn't see dof listed yet. When the curator gets around to this, I just wanted them to know that dof and hbr are indeed allelic and should be listed as such. (We exchanged alleles with Maria and Markus some time ago and all the labs have confirmed the results of the complementation tests.) . Alan Alan M. Michelson Howard Hughes Medical Institute Brigham and Women's Hospital 20 Shattuck Street Boston, MA 02115
