Subject: EDRC99 - abstract ID298
Dear Dr. Fasulo,
We are currently curating the abstracts for the upcoming European
Drosophila Research Conference in Zurich, for FlyBase. I am writing in
connection with your abstract:
'doppio fuso (duo), a gene required for spindle pole assembly during
Drosophila male meiosis'
You mention a gene that is new to FlyBase, duo.
Do you have a map location for duo? It is nice if we can keep as many
gene records as possible anchored to the map.
Also, you state that the P-element causing the duo mutation 'lies in
the 5' untranslated region of a gene that encodes a poly-A-binding
protein'.
FlyBase has a record of 3 genes encoding a poly-A-binding protein.
These are 'pAbp' (at 55B), 'Rox2' (also known as 'polyA-binding protein
II', at 44B), 'Rox8' (at 95D). Is the duo mutation in one of these 3
genes, or is it in a new poly-A-binding protein ?
Thank you for your help,
with best wishes,
Chihiro
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Chihiro Yamada.
FlyBase (Cambridge),
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Dear Dr. Yamada,
thanks for giving me the possibility to clarify my assertions:
\- duo is the mutant's name. It describes the cytological phenotype of a
polyA-binding protein allele.
\- by in situ ibridization we have positioned the P insertion at 55B.
Thank you,
with best wishes,
Barbara
Barbara Fasulo
Dipartimento di Genetica e Biologia Molecolare
Universita' di Roma 'La Sapienza'
Ple Aldo Moro 5
Roma 00185
ITALY