Date: Wed, 15 Dec 1999
From: Leonard Rabinow
1) Doa clones are lethal in both the germ-line and
soma; 2) there are 2 different protein isoforms of Doa, one of 55 and the
other of 105 kD; the 55 is nuclear and the 105 is cytoplasmic; 3) protein
and RNA expression are essentially ubiquitous throughout development, in
all tissues, although differences in expression levels exist; 4)
sex-specific expression of the kinase is essentially identical.