Losada, A., Agudo, M., Abad, J.P., Villasante, A. (1999). HeT-A telomere-specific retrotransposons in the centric heterochromatin of Drosophila melanogaster chromosome 3. Mol. Gen. Genet. 262(4/5): 618--622.
FlyBase ID
FBrf0123110
Publication Type
Research paper
Abstract
We have isolated two yeast artificial chromosome (YAC) clones from Drosophila melanogaster that contain a small amount of dodeca satellite (a satellite DNA located in the centromeric region of chromosome 3) and sequences homologous to the telomeric retro-transposon HeT-A. Using these YACs as probes for fluorescence in situ hybridization to mitotic chromosomes, we have localized these HeT-A elements to the centric heterochromatin of chromosome 3, at region h55. The possible origin of these telomeric elements in a centromeric position is discussed.