FB2026_03 , released September 17, 2026
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Spring, J. (2000.3.29). FlyBase error report for CG18144 on Wed Mar 29 02:31:28 2000. 
FlyBase ID
FBrf0128911
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Personal communication to FlyBase
Abstract
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Text of Personal Communication 
Gene or accession: CG18144
Gene annotation error
Gene CG18144 has incorrect exon/intron structure.
Comments: The region reported to code for the 15 aa gene product CG18144
contains the
bHLH (basic helix-loop-helix) Hand gene, equally similar to human paralogues
HAND1 and HAND2. As predicted by FGenes, using one of the CG18144 splice sites,
a 174 aa protein is assembled from 4 exons, with a poorly conserved (but similar
size) N-terminus, a highly conserved bHLH domain and a highly conserved
C-terminal
Hand-specific second motif (KGRTWWPxVWAxEL).
Predicted protein:
>FGENES
MFKNSVALTCEYSTMYYNSIYNTSNMFDMKHSESQVQQQIYNTSHLGYVPTSNTRIVKKR
NTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDP
KGGFRAELKPVSRKICSEKKHCLKSEIQNVPLSTKGRTGWPQDVWASELIPEHN
from AE003628: complement
1 \- 1 CDSl 55866 \- 55946
1 \- 2 CDSi 57559 \- 57714
1 \- 3 CDSi 57948 \- 58144
1 \- 4 CDSf 58294 \- 58384
Kind regards,
Jurg Spring
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    English
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