Subject: Fauvarque and Dura Polycomb enhancers and suppressors
From: Kevin Cook, Bloomington Stock Center
Subject: Fauvarque and Dura Polycomb enhancers and suppressors
I have been corresponding with Jean-Maurice Dura, CNRS Montpellier,
concerning stocks described in his paper Fauvarque and Dura, Genes and
Development  7:1508-20 , 1993 (FBrf0058522). The following FlyBase entries
need to be created or modified based on this correspondence.
1. E(Pc)14B
a. The locus E(Pc)14B (FBgn0013933) was defined by the insertion
P{418}E(Pc)14BT2.2.31 (FBti0012376/FBal0033632). Table 2 of the paper
gives its position as 14B; however, Dura says that the insertion site is
really 17B based on in situ hybridization and sequence data after PCR
rescue. Consequently, the locus name should be changed to E(Pc)17B.
b. The paper describes two alleles of E(Pc)17B: the original P{418}
insertion allele T2.2.31 and an excision allele 2.2.31. There needs to
be a FB allele entry created for 2.2.31.
c. According to Dura's correspondence, the original E(Pc)17BT2.2.31
insertion allele did not act as an Enhancer of Polycomb, but the P excision
allele E(Pc)17B2.2.31 did. It is the effect of E(Pc)17B2.2.31 that is
described in Table 3 of the paper.
d. Another excision of P{418}E(Pc)17BT2.2.31 not described in the paper,
E(Pc)17B147, behaves the same as E(Pc)17B2.2.31. An allele entry
should be created for E(Pc)17B147, since this allele will be in the
Bloomington stock collection.
2. E(Pc)35CD and su(Pc)84D
The E(Pc) and Su(Pc) names were not given in the paper. The mutations were
probably assigned these names based on the effects described in Table
3. Unfortunately, two of the loci were misnamed:
P{418}E(Pc)35CDT41.2 (FBgn0013934/FBal0033633/FBti0012373) is really a
dominant suppressor of Pc, so its name should be changed to
P{418}Su(Pc)35CDT41.2.
P{418}su(Pc)84DT66.1 (FBgn0014389/FBal0035735/FBti0012375) is really a
recessive enhancer of Pc, so its name should be changed to
P{418}e(Pc)84DET66.1.