>Subject: molybdenum coenzyme synthase I
>
>Dear Dr. Roote,
>
>Your name has been forwarded to me as a provider of annotations for the
>Drosophila genome. In this capacity, you may be interested to know that we
>have recently published a paper that describes the alternative splicing of
>the molybdenum coenzyme synthase I (MOCSI) locus in many species (see RNA
> 6:928-936 ). All of the species produce a bicistronic transcript containing
>separate adjacent open reading frames for MOCS1A and MOCS1B, and all
>species also produce mRNA splice forms that fuse the ORFs to encode a
>single fused MOCS1A-MOCS1B protein. The present genomic annotation for the
>Drosophila locus (AC006562.8) predicts the fused form, but not the
>bicistronic form. If our GenBank depositions would be useful, they are
>AF24021 for the Drosophila bicistronic splice form and AF24027 for the
>fused splice form.
>
>Yours sincerely,
>
>Todd A. Gray, Ph.D.
>Department of Genetics
>Case Western Reserve University