Subject: Helping FlyBase: ADRC-10330
Dear David,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'necrotic mutations homologous to disease-associated varients in human serpins.'
You mention a gene that is new to FlyBase, Spn43Ad. Do you know which of the
Genome Project CG annotations your gene corresponds to? All the CGs
have corresponding gene records in FlyBase already and we don't like to
make duplicate records for what is actually the same gene unless we
can't avoid it. If your gene does not correspond to a CG then perhaps
you could tell me its map location, as this is valuable information for
the genome annotation project.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10330
Rachel,
43Ad is a serpin in the 43A cluster that we missed from our
sequencing or cDNAs. It was clear as a transcript between 43Ab and 43Ac, ie
within the 5' pk intron. We have a projectile working on it, who hopefully
will have the cDNA fully sequenced soon. At first sight it looks like a
non-inhibitory serpin. We will let you have full details soon.
David Gubb
Department of Genetics
University of Cambridge
Downing Street
CB2 3EH UK