Subject: Helping FlyBase: ADRC-10313
Dear Savita,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'achintya and vismay: two novel, tandem-repeated TALE-class homeobox genes.'
You mention two genes that are new to FlyBase, achintya and vismay. Do
you know which of the Genome Project CG annotations your genes
correspond to? All the CGs have corresponding gene records in FlyBase
already and we don't like to make duplicate records for what is
actually the same gene unless we can't avoid it. If your genes do not
correspond to CGs then perhaps you could tell me their map location, as
this is valuable information for the genome annotation project. Also \-
we like to keep Etymology statements for genes with distinctive names.
Would you be able to explain the origin of the achintya and vismay
names so thatwe can explain them in FlyBase?
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10313
Hi Rachel,
Here is the information you requested:
achintya: CG8819 (49A10-12 with EP(2)2107 inserted in 5'-UTR)
vismay: CG8821 (49A10)
As part of my project, I wanted to understand the function of Drosophila
TGIF. A locus at 49A10 seemed to encode a batch of ESTs with a high
degree of homology to vertebrate TGIFs. However, my initial results were
difficult to explain. I therefore named this locus 'achintya', which is a
Sanskrit word meaning inconceivable or beyond thought. When the genome
sequence was published, it became clear that I was actually dealing with
a tandem-duplication. I therefore named CG8821 as 'vismay', which in Hindi
means surprise.
I hope this provides the answers you're looking for. Good luck with the
curation.
Regards,
Savita.
Savita Ayyar, Research Scholar
Department of Anatomy
University of Cambridge,
Cambridge CB2 3DY