Subject: Helping FlyBase: ADRC-10154
Dear Dominique,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'Genetic analysis of the Drosophila innate immune response.'
You mention two genes that are new to FlyBase, shadok and galere. Do
you know which of the Genome Project CG annotations your genes
correspond to? All the CGs have corresponding gene records in FlyBase
already and we don't like to make duplicate records for what is
actually the same gene unless we can't avoid it. If your genes do not
correspond to CGs then perhaps you could tell me their map location, as
this is valuable information for the genome annotation project.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10154
Dear Rachel,
shadok and galere are two genes found in our screen. Even though the shadok
mutations did complement immune deficiency (imd) in our reporter assay, we
found that shadok and immune deficiency affect the same gene (BG5 in BDGP)
and I guess they should all be called imd. The cloning of the imd mutation
has been performed by P. Georgel and Sylvia Naiza working with Jean-Marc
Reichhart in Jules Hoffmann's lab.
Regarding galere, we are currently trying to clone it. However, since we
are collaborating with a private partner, we are bound by a nondisclosure
clause in our contract and therefore I am not allowed to tell you where it
maps. However, as soon as I'll get the authorization, I will let you know
what it is. Sorry about this.
Best wishes
Dominique