Subject: Helping FlyBase: ADRC-10489
Dear Joseph,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'The kinesin-associated protein Dunc-76 is required for axonal transport in
the larval nervous system.'
You mention a gene that is new to FlyBase, Unc-76. Do you know which
of the Genome Project CG annotations your gene corresponds to? All the
CGs have corresponding gene records in FlyBase already and we don't
like to make duplicate records for what is actually the same gene
unless we can't avoid it. If your gene does not correspond to a CG
then perhaps you could tell me its map location, as this is valuable
information for the genome annotation project.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10489
Dear Rachel,
Drosophila unc-76 (Dunc-76 or Unc-76, if you prefer I call it that)
corresponds to CG3981. It is just distal to csw (the 3'end of
Dunc-76 is about 1kb 5' of the csw transcription start site.
Interestingly, in the first genome annotation CG3981 had a large
(about 14kb) intron. In the second version of Gadfly, however, this
intron is shown as intergenic space, and CG3981 is split into two
genes. We think that the first version (one big gene, not two small
genes) is correct. Let me know if you have any questions.
Best Regards,
Joe
Rachel Drysdale (Genetics) wrote: