Gene or accession: LD22117
Release: 2
cDNA or EST error
Comments: In AE003451, nucleotides 34'106-34'699 contains an ORF which
is 98% homologous with Ras small GTPases such as CG2532 gene. No gene
is currently identified at this site, just 3' of LD22117 (CG1619). It
is possible that this new Ras small GTPase gene should be merged with
LD22117. this gene should be on the plus strand, between the annotated
genes spri and  BcDNA:LD22117 . Evidence for the presence of a strong
homology between this new gene and genes now known as CG2532, CG9807
and CG2885 (all encoding small GTPases) was reported in Hutter and
Karch (Experientia  50:749-762 , 1994). I should stress that this
sequence is also present near the CG2111 gene, again where no Ras small
GTPase gene is identified yet.
Pierre Hutter
Subject: cDNA Small Rab GTPase gene in AE003451 (nt 106042-106636)
Dear Gillian, Dear Sima,
Just one more thing. In my first e-mail about the new small GTPase gene
between the annotated genes spri and  BcDNA:LD22117 , I had mentioned another
nearby site which harbours an unidentified small Rab GTPase gene between
CG9806 and CG2111 (on AE003451 scaffold as well). I cannot work out its
genomic structure but when the AE003451 scaffold will be reannotated, nt
106042-106636 (referring to release 2.0) should definitely also be
investigated for homologies to other Ras GTPases, EST sequences etc.
..
Many thanks again for your assistance, Pierre
Dr Pierre Hutter
Unit of Genetics
Institut Central des Hopitaux Valaisans
Av.Grand-Champsec 86
1951 SION
Switzerland