Subject: Helping FlyBase: CSH-201
Dear Jakob-Andreas,
We are currently curating the abstracts for the 2001 CSH Neurobiology
of Drosophila Conference, for FlyBase.
I am writing in connection with your abstract:
'The drosophila mutant lochrig (loe) \- neurodegeneration and
cholesterol metabolism.'
You mention a gene that is new to FlyBase, loe. Do you know which of the
Genome Project CG annotations your gene corresponds to? All the CGs
have corresponding gene records in FlyBase already and we don't like to
make duplicate records for what is actually the same gene unless we
can't avoid it. If your gene does not correspond to a CG then perhaps
you could tell me its map location, as this is valuable information for
the genome annotation project.
Thank you very much for your help,
with best wishes,
Rachel.
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Rachel Drysdale, Ph.D.
FlyBase (Cambridge),
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Subject: Re: Helping FlyBase: CSH-201
Dear Rachel,
yes, I know which gene prediction corresponds to the loe mutant: It
is the gamma subunit of the AMP activated protein kinase complex
in Drosophila (as mentioned in the abstract...) In the databases
this is registered as SNF4Agamma or AMPK gamma. For this
SNF4 protein a predicted sequence already exists in
FlyBase, based on a sequence published by Yoshida et al 1999.
The gene annotation has got the number CG17299.
...
with best regards,
Jakob
Jakob-Andreas Tschaepe
Dept. of Genetics and Neurobiology
AG Pflugfelder
University of Wuerzburg
Biozentrum Am Hubland
97074 Wuerzburg
Germany