The gene product of shanti (FBgn0031260 ) was recently identified as
orthologue of the human intramembrane cleaving presenilin-type aspartic
protease  signal peptide peptidase
Weihofen A, Binns K, Lemberg MK, Ashman K, Martoglio B.
Identification of signal peptide peptidase, a presenilin-type aspartic
protease.
Science. 2002 Jun 21;296(5576):2215-8.
Kind regards
Andreas Weihofen
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Andreas Weihofen
Institute of Biochemistry
ETH Hoenggerberg
8093 Zurich
Switzerland