Subject: Helping FlyBase: ADRC-10171 Dear Gary, We are currently curating the abstracts for the upcoming 44th (Chicago) Annual Drosophila Research Conference, for FlyBase. I am writing in connection with your abstract: A search for doxycycline-dependent mutations that increase Drosophila life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cct1 genes. You mention a gene symbol that is new to FlyBase, Sugar-baby. Do you know which of the Genome Project CG annotations your gene corresponds to? All the CGs have corresponding gene records in FlyBase already and we don't like to make duplicate records for what is actually the same gene unless we can't avoid it. You also mention Red-herring, in the intron of enc. The Release 3 genome annotation for enc shows no intronic gene, so we have missed this one. The gene models for Red-herring and enc need to be incorporated into the genome annotation. It would be great if you could submit the gene structure information to FlyBase, either by using the update form for the genome annotation for enc e.g. at http://www.fruitfly.org/cgi-bin/annot/fban?FBan0010847 or by submitting to me or flybase-help the sequences for the genes. These will be fed into the pipeline for reannotation of enc and be taken into account when it is next updated. Thank you very much for your help, with best wishes, Rachel. \---------------------------------------------------------------------- Rachel Drysdale, Ph.D. FlyBase (Cambridge), \---------------------------------------------------------------------- Subject: Re: Helping FlyBase: ADRC-10171 Dear Rachel, We just published an article in Genome Biology Online 'A search for doxycycline-dependent mutations that increase Drosophila life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cct1 genes', which explains all the things you want to know, with maps! Please see G.Landis, D. Bhole, and J.Tower in the recent edition of that journal. There is other info in there that you will want to know as well. Sincerely, Gary Landis. P.S.-Sugary Baby corresponds to CG7334
