Beller, M., Blanke, S., Brentrup, D., Jackle, H. (2002). Identification and expression of Ima, a novel Ral-interacting Drosophila protein.  Gene Expr. Patterns 2(3-4): 289--296.

FBrf0157222

Research paper

We report the identification of Ima, a novel Drosophila MAGUK-like protein, which contains two WW and four PDZ protein interaction domains and interacts with the small GTPase dRal in the yeast two-hybrid system and pull-down assays. The gene is expressed in distinct spatiotemporal patterns throughout embryonic development. Overexpression of Ima interferes with normal Drosophila development, indicating that the gene functions in a tissue specific manner.