Gene or accession: CG1712
Release: 3
Gene annotation error
Gene CG1712 has incorrect exon/intron structure or translation start site.
Gene cDNA sequence:
>DmGr43a.cDNa
ATGGAGATATCCCAGCCCAGCATCGGCATCTTCTACATCAGCAAAGTGCTGGCCCTGGCTCCATATGCTACGGTCCGGA
ACTCCAAGGGCCGGGTGGAAATTGGTCGCAGCTGGCTCTTCACTGTATACTCGGCCACATTAACGGTGGTTATGGTTTT
TCTCACTTATCGGGGTCTCCTGTTCGATGCTAACTCCGAAATTCCCGTGCGAATGAAGTCGGCTACGTCGAAGGTGGTG
ACGGCCCTGGACGTGTCTGTGGTGGTCATGGCCATTGTATCCGGTGTTTACTGTGGCCTTTTCAGCCTGAACGACACTC
TCGAGCTCAACGATCGACTAAACAAGATCGATAATACCCTAAATGCCTACAATAACTTTCGAAGAGATCGATGGCGAGC
CTTGGGCATGGCTGCCGTCTCTCTGCTGGCCATTTCGATTCTGGTCGGCCTGGATGTAGGGACGTGGATGCGCATTGCC
CAGGATATGAACATAGCTCAGTCGGATACGGAGCTCAATGTGCACTGGTACATTCCATTCTATAGTCTTTACTTCATCC
TCACGGGCTTGCAGGTTAACATTGCCAACACGGCCTATGGACTAGGAAGGCGCTTTGGCCGTCTGAACCGAATGCTTTC
GAGCAGCTTTCTTGCAGAGAACAATGCAACCAGTGCCATCAAGCCACAAAAGGTCAGCACCGTGAAGAACGTTAGCGTA
AATCGGCCAGCGATGCCATCGGCACTCCACGCGAGCCTGACGAAGCTGAACGGCGAAACCTTGCCCAGTGAAGCCGCAG
CCAAGAACAAGGGGTTGCTCCTCAAATCCCTGGCGGACAGTCACGAGTCGCTGGGAAAATGTGTCCACCTCCTGTCCAA
CTCCTTCGGCATTGCGGTTCTCTTCATCCTGGTGTCCTGTCTGCTGCACCTCGTGGCTACGGCCTACTTCCTCTTTCTG
GAACTGCTCAGCAAGCGGGATAACGGCTACCTGTGGGTGCA!
GATGCTCTGGATTTGCTTTCACTTCCTGCGACTGCTCATGGTGGTGGAGCCGTGCCACTTGGCTGCCCGAGAGTCCCG
TAAAACGATCCAGATTGTTTGCGAAATCGAGCGGAAAGTGCACGAGCCCATTCTCGCGGAGGCAGTTAAGAAGTTTTGG
CAGCAGTTACTCGTCGTAGATGCTGACTTCTCCGCCTGCGGATTGTGCCGCGTGAACCGCACCATTCTGACATCGTTTG
CATCCGCCATAGCCACCTATCTCGTGATTCTCATTCAGTTTCAACGGACCAATGGCTAA
Protein sequence:
>DmGr43a
MEISQPSIGIFYISKVLALAPYATVRNSKGRVEIGRSWLFTVYSATLTVVMVFLTYRGLLFDANSEIPVRMKSATSKVVT
ALDVSVVVMAIVSGVYCGLFSLNDTLELNDRLNKIDNTLNAYNNFRRDRWRALGMAAVSLLAISILVGLDVGTWMRIAQD
MNIAQSDTELNVHWYIPFYSLYFILTGLQVNIANTAYGLGRRFGRLNRMLSSSFLAENNATSAIKPQKVSTVKNVSVNRP
AMPSALHASLTKLNGETLPSEAAAKNKGLLLKSLADSHESLGKCVHLLSNSFGIAVLFILVSCLLHLVATAYFLFLELLS
KRDNGYLWVQMLWICFHFLRLLMVVEPCHLAARESRKTIQIVCEIERKVHEPILAEAVKKFWQQLLVVDADFSACGLCRV
NRTILTSFASAIATYLVILIQFQRTNG
Comments: Comparison with D. pseudoobscura reveals an intron near the
C-terminus that is open and in frame, but which is not open or in-frame in Dp,
hence it should be spliced in the Dm annotation too. This removes an others
unalignable expansion region in this protein relative to the rest of the Gr
family.