Gene or accession: CG7189
Release: 3
Gene annotation error
Gene CG7189 has incorrect exon/intron structure or translation start site.
Gene cDNA sequence:
>Gr66a
ATGGACAACATGGCGCAGGCGGAGGACGCAGTGCAACCACTATTGCAGCAGTTCCAGCAACTGTTCTTCATATCCAAGAT
AGCTGGAATTCTGCCACAGGATCTCGAGAAGTTTCGATCTAGGAATCTGCTGGAGAAATCCCGTAATGGCATGATTTACA
TGCTGAGTACTTTAATACTCTACGTTGTGCTCTATAATATTTTGATATATTCCTTTGGAGAGGAGGACCGCAGCCTAAAG
GCCTCGCAGAGCACCTTGACTTTCGTGATTGGCTTGTTCCTGACCTATATCGGTCTGATTATGATGGTCTCCGACCAGTT
GACCGCGTTACGAAACCAGGGTAGAATTGGAGAGCTTTACGAGCGCATCCGTCTGGTGGATGAGCGCCTTTACAAAGAGG
GGTGTGTTATGGACAACAGTACAATTGGACGGCGCATACGAATTATGCTGATCATGACGGTCATCTTTGAGTTGTCCATT
TTGGTGAGCACCTATGTCAAGCTGGTGGACTATAGTCAATGGATGTCCTTGTTATGGATAGTGTCCGCCATTCCCACGTT
CATCAACACGCTAGACAAGATCTGGTTCGCTGTTTCGTTATATGCGTTGAAAGAACGCTTCGAGGCCATAAACGCCACCC
TAGAGGAACTGGTGGACACGCACGAGAAGCATAAGCTGTGGCTGCGAGGCAATCAAGAGGTTCCGCCTCCTCTGGACAGC
TCCCAGCCGCCTCAGTATGACAGCAACCTGGAGTATCTGTACAAGGAACTAGGAGGTATGGACATAGGTTCCATTGGCAA
GAGTTCAGTGTCTGGTTCGGGGAAAAACAAAGTAGCACCAGTGGCCCACTCCATGAACTCCTTTGGTGAAGCAATTGATG
CGGCCAGCAGGAAGCCTCCACCGCCTCCCCTGGCCACTAACATGGTCCATGAAAGCGAGCTGGGAAATGCCGCTAAGGTA
GAGGAGAAACTAAACAACCTGTGCCAGGTGCACGACGAGATCTGTGAAATCGGAAAAGCTTTGAACGAGCTGTGGAGCTA
TCCCATTCTATCTCTAATGGCCTATGGTTTTCTGATTTTCACTGCTCAACTTTATTTCCTCTACTGCGCTACACAGTACC
AATCGATACCATCGCTTTTCCGTTCCGCCAAGAATCCCTTCATCACTGTTATAGTTCTAAGTTATACGTCTGGAAAATGC
GTGTACCTCATCTACCTGAGTTGGAAAACGTCGCAGGCCTCCAAGCGCACAGGAATCAGTCTGCACAAATGTGGCGTGGT
GGCCGATGATAATCTTCTCTACGAAATTGTTAACCACCTATCGCTAAAATTGCTCAACCACTCGGTGGACTTTTCGGCTT
GCGGCTTCTTTACCCTGGACATGGAAACATTGTATGGTGTGAGTGGCGGGATCACTAGCTACCTGATCATCCTGATTCAG
TTCAATTTGGCCGCCCAGCAGGCCAAAGAGGCTATACAGACGTTCAACTCGCTTAATGACACCGCCGGCTTGGTTGGTGC
CGCCACCGATATGGATAATATTAGCTCCACGCTGCGTGATTTCGTCACCACGACCATGACACCGGCGGTCTAA
Protein sequence:
>Gr66a
MDNMAQAEDAVQPLLQQFQQLFFISKIAGILPQDLEKFRSRNLLEKSRNGMIYMLSTLILYVVLYNILIYSFGEEDRSLK
ASQSTLTFVIGLFLTYIGLIMMVSDQLTALRNQGRIGELYERIRLVDERLYKEGCVMDNSTIGRRIRIMLIMTVIFELSI
LVSTYVKLVDYSQWMSLLWIVSAIPTFINTLDKIWFAVSLYALKERFEAINATLEELVDTHEKHKLWLRGNQEVPPPLDS
SQPPQYDSNLEYLYKELGGMDIGSIGKSSVSGSGKNKVAPVAHSMNSFGEAIDAASRKPPPPPLATNMVHESELGNAAKV
EEKLNNLCQVHDEICEIGKALNELWSYPILSLMAYGFLIFTAQLYFLYCATQYQSIPSLFRSAKNPFITVIVLSYTSGKC
VYLIYLSWKTSQASKRTGISLHKCGVVADDNLLYEIVNHLSLKLLNHSVDFSACGFFTLDMETLYGVSGGITSYLIILIQ
FNLAAQQAKEAIQTFNSLNDTAGLVGAATDMDNISSTLRDFVTTTMTPAV
Comments: Comparison with D. pseudoobscura suggests that the second phase 1
intron, which is open and in frame, is not real. It encodes amino acids that
align well with those encoded by Dp. Remarkably the Dp gene has a unique phase
1 intron of its own (for real with stop codons and a frameshift) in this region.