FB2026_03 , released September 17, 2026
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Citation
Michelson, A.M. (2003). Running interference for hedgehog signaling.  Sci. STKE 2003(192): PE30.
FlyBase ID
FBrf0160795
Publication Type
Note
Abstract
The new technology of RNA interference (RNAi) is allowing high-throughput screening of cells to examine many biological processes. Michelson discusses one such system in which the Drosophila Hedgehog (Hh) pathway was analyzed by systematic genome-wide RNAi analysis. The results not only suggest unexpected overlap in the Hh and Wingless (Wg) pathways, but also provide proof of principle for the development of high-throughput assays using RNAi techniques.
PubMed ID
12881613
PubMed Central ID
DOI
10.1126/stke.2003.192.pe30
Related Publication(s)
Research paper

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.
Lum et al., 2003, Science 299(5615): 2039--2045 [FBrf0159322]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Sci. STKE
    Title
    Science's STKE: Signal Transduction Knowledge Environment
    Publication Year
    1999-
    ISBN/ISSN
    1525-8882
    Data From Reference